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Assessing Causal Relationship Between Human Blood Metabolites and Five Neurodegenerative Diseases With GWAS Summary Statistics

Background: Neurodegenerative diseases (NDDs) are the leading cause of disability worldwide while their metabolic pathogenesis is unclear. Genome-wide association studies (GWASs) offer an unprecedented opportunity to untangle the relationship between metabolites and NDDs. Methods: By leveraging two-...

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Detalles Bibliográficos
Autores principales: Chen, Haimiao, Qiao, Jiahao, Wang, Ting, Shao, Zhonghe, Huang, Shuiping, Zeng, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8695771/
https://www.ncbi.nlm.nih.gov/pubmed/34955704
http://dx.doi.org/10.3389/fnins.2021.680104