Metabolomic Profiling Identifies Exogenous and Microbiota-Derived Metabolites as Markers of Methotrexate Efficacy in Juvenile Idiopathic Arthritis

Variability in methotrexate (MTX) efficacy represents a barrier to early and effective disease control in the treatment of juvenile idiopathic arthritis (JIA). This work seeks to understand the impact of MTX on the plasma metabolome and to identify metabolic biomarkers of MTX efficacy in a prospecti...

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Detalles Bibliográficos
Autores principales: Funk, Ryan Sol, Becker, Mara L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8695929/
https://www.ncbi.nlm.nih.gov/pubmed/34955838
http://dx.doi.org/10.3389/fphar.2021.768599

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8695929/
https://www.ncbi.nlm.nih.gov/pubmed/34955838
http://dx.doi.org/10.3389/fphar.2021.768599

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