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Dual sEH/COX-2 Inhibition Using PTUPB—A Promising Approach to Antiangiogenesis-Induced Nephrotoxicity

Kidney injury from antiangiogenic chemotherapy is a significant clinical challenge, and we currently lack the ability to effectively treat it with pharmacological agents. Thus, we set out to investigate whether simultaneous soluble epoxide hydrolase (sEH) and cyclooxygenase-2 (COX-2) inhibition usin...

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Detalles Bibliográficos
Autores principales: Jankiewicz, Wojciech K., Barnett, Scott D., Stavniichuk, Anna, Hwang, Sung Hee, Hammock, Bruce D., Belayet, Jawad B., Khan, A. H., Imig, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8695932/
https://www.ncbi.nlm.nih.gov/pubmed/34955823
http://dx.doi.org/10.3389/fphar.2021.744776