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Dual sEH/COX-2 Inhibition Using PTUPB—A Promising Approach to Antiangiogenesis-Induced Nephrotoxicity
Kidney injury from antiangiogenic chemotherapy is a significant clinical challenge, and we currently lack the ability to effectively treat it with pharmacological agents. Thus, we set out to investigate whether simultaneous soluble epoxide hydrolase (sEH) and cyclooxygenase-2 (COX-2) inhibition usin...
Autores principales: | Jankiewicz, Wojciech K., Barnett, Scott D., Stavniichuk, Anna, Hwang, Sung Hee, Hammock, Bruce D., Belayet, Jawad B., Khan, A. H., Imig, John D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8695932/ https://www.ncbi.nlm.nih.gov/pubmed/34955823 http://dx.doi.org/10.3389/fphar.2021.744776 |
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