Development and validation of a sensitive LC-MS/MS method for pioglitazone: application towards pharmacokinetic and tissue distribution study in rats

In the present study, a sensitive LC-MS/MS method was developed and validated to measure pioglitazone (PGZ) concentrations in rat plasma and tissues. The chromatographic separation was achieved by using a YMC Pro C(18) column (100 mm × 4.6 mm, 3μ) with a mobile phase consisting of formic acid (0.1%...

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Detalles Bibliográficos
Autores principales: G., Kusuma Kumari, Thaggikuppe Krishnamurthy, Praveen, Ammu V. V. V., Ravi Kiran, Vishwanath, Kurawattimath, Narenderan, S. T., Babu, B., Krishnaveni, Nagappan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8695949/
https://www.ncbi.nlm.nih.gov/pubmed/35423625
http://dx.doi.org/10.1039/d1ra01126j

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8695949/
https://www.ncbi.nlm.nih.gov/pubmed/35423625
http://dx.doi.org/10.1039/d1ra01126j

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