Spectroscopic sensing and quantification of AP-endonucleases using fluorescence-enhancement by cis–trans isomerization of cyanine dyes

Apurinic/apyrimidinic (AP) endonucleases are vital DNA repair enzymes, and proposed to be a prognostic biomarker for various types of cancer in humans. Numerous DNA sensors have been developed to evaluate the extent of nuclease activity but their DNA termini are not protected against other nucleases...

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Detalles Bibliográficos
Autores principales: Cho, JunHo, Oh, Sanghoon, Lee, DongHun, Han, Jae Won, Yoo, Jungmin, Park, Daeho, Lee, Gwangrog
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8695990/
https://www.ncbi.nlm.nih.gov/pubmed/35423644
http://dx.doi.org/10.1039/d0ra08051a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8695990/
https://www.ncbi.nlm.nih.gov/pubmed/35423644
http://dx.doi.org/10.1039/d0ra08051a

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