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Public Immunity: Evolutionary Spandrels for Pathway-Amplifying Protective Antibodies
Humoral immunity is seeded by affinity between the B cell receptor (BCR) and cognate antigen. While the BCR is a chimeric display of diverse antigen engagement solutions, we discuss its functional activity as an ‘innate-like’ immune receptor, wherein genetically hardwired antigen complementarity can...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8696009/ https://www.ncbi.nlm.nih.gov/pubmed/34956170 http://dx.doi.org/10.3389/fimmu.2021.708882 |