Conformational Changes in a Macrolide Antibiotic Binding Protein From Mycobacterium smegmatis Upon ADP Binding

Rv3197 (MABP-1), a non-canonical ABC protein in Mycobacterium tuberculosis, has ATPase activity and confers inducible resistance to the macrolide family of antibiotics. Here we have shown that MSMEG_1954, the homolog of Rv3197 in M. smegmatis, has a similar function of conferring macrolide resistanc...

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Detalles Bibliográficos
Autores principales: Zhang, Qingqing, Liu, Xiang, Liu, Huijuan, Zhang, Bingjie, Yang, Haitao, Mi, Kaixia, Guddat, Luke W., Rao, Zihe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8696161/
https://www.ncbi.nlm.nih.gov/pubmed/34956144
http://dx.doi.org/10.3389/fmicb.2021.780954

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8696161/
https://www.ncbi.nlm.nih.gov/pubmed/34956144
http://dx.doi.org/10.3389/fmicb.2021.780954

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