Importance of SNP Dependency Correction and Association Integration for Gene Set Analysis in Genome-Wide Association Studies

A typical genome-wide association study (GWAS) analyzes millions of single-nucleotide polymorphisms (SNPs), several of which are in a region of the same gene. To conduct gene set analysis (GSA), information from SNPs needs to be unified at the gene level. A widely used practice is to use only the mo...

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Detalles Bibliográficos
Autores principales: Marczyk, Michal, Macioszek, Agnieszka, Tobiasz, Joanna, Polanska, Joanna, Zyla, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8696167/
https://www.ncbi.nlm.nih.gov/pubmed/34956320
http://dx.doi.org/10.3389/fgene.2021.767358

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8696167/
https://www.ncbi.nlm.nih.gov/pubmed/34956320
http://dx.doi.org/10.3389/fgene.2021.767358

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