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Airway Basal Cells Mediate Hypoxia-Induced EMT by Increasing Ribosome Biogenesis

Excessive secretion of airway mucus and fluid accumulation are the common features of many respiratory diseases, which, in turn, induce cell hypoxia in the airway epithelium, resulting in epithelial–mesenchymal transition (EMT) and ultimately fibrosis. However, the mechanisms of EMT induced by hypox...

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Detalles Bibliográficos
Autores principales: Hou, Yapeng, Ding, Yan, Du, Danni, Yu, Tong, Zhou, Wei, Cui, Yong, Nie, Hongguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8696177/
https://www.ncbi.nlm.nih.gov/pubmed/34955855
http://dx.doi.org/10.3389/fphar.2021.783946