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Genetic Modification of Limbal Stem Cells to Decrease Allogeneic Immune Responses

Limbal stem cell (LSC) transplantation is the only efficient treatment for patients affected by LSC deficiency (LSCD). Allogeneic LSC transplantation is one of the most successful alternative for patients with bilateral LSCD. Nevertheless, the high variability of the human leukocyte antigens (HLA) r...

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Detalles Bibliográficos
Autores principales: Valdivia, Emilio, Bertolin, Marina, Breda, Claudia, Carvalho Oliveira, Marco, Salz, Anna Katharina, Hofmann, Nicola, Börgel, Martin, Blasczyk, Rainer, Ferrari, Stefano, Figueiredo, Constanca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8696204/
https://www.ncbi.nlm.nih.gov/pubmed/34956181
http://dx.doi.org/10.3389/fimmu.2021.747357