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Engineering the biomimetic cofactors of NMNH for cytochrome P450 BM3 based on binding conformation refinement
Cytochrome P450 BM3 (BM3) is an important oxidoreductase that is widely used in drug synthesis, chemical synthesis, and other industries. However, as BM3 unquestionably increases costs by consuming a natural cofactor that unstably provides electrons, an alternative biomimetic cofactor with simpler s...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8696588/ https://www.ncbi.nlm.nih.gov/pubmed/35423749 http://dx.doi.org/10.1039/d1ra00352f |