Engineering the biomimetic cofactors of NMNH for cytochrome P450 BM3 based on binding conformation refinement

Cytochrome P450 BM3 (BM3) is an important oxidoreductase that is widely used in drug synthesis, chemical synthesis, and other industries. However, as BM3 unquestionably increases costs by consuming a natural cofactor that unstably provides electrons, an alternative biomimetic cofactor with simpler s...

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Detalles Bibliográficos
Autores principales: Liu, Yao, Cong, Yalong, Zhang, Chuanxi, Fang, Bohuan, Pan, Yue, Li, Qiangzi, You, Chun, Gao, Bei, Zhang, John Z. H., Zhu, Tong, Zhang, Lujia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8696588/
https://www.ncbi.nlm.nih.gov/pubmed/35423749
http://dx.doi.org/10.1039/d1ra00352f

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