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Crim1 and Kelch-like 14 exert complementary dual-directional developmental control over segmentally specific corticospinal axon projection targeting

The cerebral cortex executes highly skilled movement, necessitating that it connects accurately with specific brainstem and spinal motor circuitry. Corticospinal neurons (CSN) must correctly target specific spinal segments, but the basis for this targeting remains unknown. In the accompanying report...

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Detalles Bibliográficos
Autores principales: Sahni, Vibhu, Itoh, Yasuhiro, Shnider, Sara J., Macklis, Jeffrey D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8697027/
https://www.ncbi.nlm.nih.gov/pubmed/34686337
http://dx.doi.org/10.1016/j.celrep.2021.109842