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A reduction-responsive drug delivery with improved stability: disulfide crosslinked micelles of small amiphiphilic molecules
Micelles self-assembled from small amphiphilic molecules are unstable in biological fluids, and thus are poor drug carriers. In contrast, amphiphilic polymer micelles can encapsulate hydrophobic drugs in their core to greatly enhance their aqueous solubility and extend their retention time in blood...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8697188/ https://www.ncbi.nlm.nih.gov/pubmed/35423790 http://dx.doi.org/10.1039/d1ra00079a |