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Knockdown of insulin-like growth factor 2 gene disrupts mitochondrial functions in the liver

Even though insulin-like growth factor 2 (IGF2) has been reported to be overexpressed in nonalcoholic fatty liver disease (NAFLD), its role in the progression of NAFLD and the potential mechanism remain largely unclear. Using in vitro models, we found that IGF2 was the key overexpressed gene in stea...

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Detalles Bibliográficos
Autores principales: Gui, Weiwei, Zhu, Yiyi, Sun, Shuiya, Zhu, Weifen, Tan, Bowen, Zhao, Hanxin, Shang, Chengxin, Zheng, Fenping, Lin, Xihua, Li, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8697341/
https://www.ncbi.nlm.nih.gov/pubmed/33988719
http://dx.doi.org/10.1093/jmcb/mjab030