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Regulation of divalent metal ions to the aggregation and membrane damage of human islet amyloid polypeptide oligomers
The accumulation of human islet amyloid polypeptide (hIAPP) on the surface of pancreatic β cells is closely related to the death of the cells. Divalent metal ions play a significant role in the cytotoxicity of hIAPP. In this study, we examined the roles played by the divalent metal ions of zinc, cop...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8697352/ https://www.ncbi.nlm.nih.gov/pubmed/35423832 http://dx.doi.org/10.1039/d1ra00354b |