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Improvement in Ionization Efficiency Using Metal Oxide Nanoparticles in Laser Desorption/Ionization Mass Spectrometry of a Cancer Drug

Mass spectrometry imaging (MSI) without labeling has the potential for faster screening in drug development. Matrix-assisted laser desorption/ionization (MALDI) is typically used, but it has a large matrix size and uneven drug distribution. Surface-assisted laser desorption/ionization (SALDI) using...

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Detalles Bibliográficos
Autores principales: Kannen, Hiroki, Miyoshi, Yuto, Hazama, Hisanao, Awazu, Kunio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Mass Spectrometry Society of Japan 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8697360/
https://www.ncbi.nlm.nih.gov/pubmed/34993048
http://dx.doi.org/10.5702/massspectrometry.A0099