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Talin in mechanotransduction and mechanomemory at a glance
Talins are cytoskeletal linker proteins that consist of an N-terminal head domain, a flexible neck region and a C-terminal rod domain made of 13 helical bundles. The head domain binds integrin β-subunit cytoplasmic tails, which triggers integrin conformational activation to increase affinity for ext...
Autores principales: | Goult, Benjamin T., Brown, Nicholas H., Schwartz, Martin A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8697387/ https://www.ncbi.nlm.nih.gov/pubmed/34708856 http://dx.doi.org/10.1242/jcs.258749 |
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