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A novel targeted co-delivery nanosystem for enhanced ovarian cancer treatment via multidrug resistance reversion and mTOR-mediated signaling pathway

BACKGROUND: Multidrug resistance (MDR) is the main challenge of successful chemotherapy for ovarian cancer patients, with 50% to 75% of ovarian cancer patients eventually relapsed due to it. One of the effective strategies for treating MDR and improving therapeutic efficiency of ovarian cancer is to...

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Detalles Bibliográficos
Autores principales: Wang, Xueqin, Xiong, Tiandi, Cui, Miao, Li, Na, Li, Qin, Zhu, Li, Duan, Shaofeng, Wang, Yunlong, Guo, Yuqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8697442/
https://www.ncbi.nlm.nih.gov/pubmed/34949180
http://dx.doi.org/10.1186/s12951-021-01139-1