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Identification of a covalent binder to the oncoprotein gankyrin using a NIR-Based OBOC screening method
Despite huge advancements in the process of synthesizing small molecules as part of one-bead-one-compound (OBOC) libraries, progress lags in the ability to screen these libraries against proteins of interest. Recently, we developed a method to screen OBOC libraries in which a target protein is label...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8697547/ https://www.ncbi.nlm.nih.gov/pubmed/35423814 http://dx.doi.org/10.1039/d0ra10976b |