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Regioselective Pd-catalyzed α-alkylation of furans using alkyl iodides

Herein, direct alkylation of the C–H bond at the α-position of furans catalyzed by palladium catalyst is reported. This protocol targets α-alkylfurans, achieving moderate to good yields under very practical reaction conditions. With a broad scope of substrates and good functional group tolerance, th...

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Detalles Bibliográficos
Autores principales: Yuan, Jiaqi, Zhang, Xiaofei, Yang, Chunhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8697702/
https://www.ncbi.nlm.nih.gov/pubmed/35423913
http://dx.doi.org/10.1039/d1ra01522b