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Tailoring amphotericin B as an ionic liquid: an upfront strategy to potentiate the biological activity of antifungal drugs

Aspergillus species are the primary cause of invasive aspergillosis, which afflicts hundreds of thousands of patients yearly, with high mortality rates. Amphotericin B is considered the gold standard in antifungal drug therapy, due to its broad-spectrum activity and rarely reported resistance. Howev...

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Detalles Bibliográficos
Autores principales: Hartmann, Diego O., Shimizu, Karina, Rothkegel, Maika, Petkovic, Marija, Ferraz, Ricardo, Petrovski, Željko, Branco, Luís C., Canongia Lopes, José N., Silva Pereira, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8697833/
https://www.ncbi.nlm.nih.gov/pubmed/35423994
http://dx.doi.org/10.1039/d1ra00234a