Target-AID-Mediated Multiplex Base Editing in Porcine Fibroblasts

SIMPLE SUMMARY: CRISPR/Cas9 driven multiplex genome editing may induce genotoxicity and chromosomal rearrangements due to DNA double-strand breaks at multiple loci simultaneously. To overcome this problem in porcine cells we utilized Target-AID, a base editing system, to edit multiple loci in the po...

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Detalles Bibliográficos
Autores principales: Yum, Soo-Young, Jang, Goo, Koo, Okjae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8697861/
https://www.ncbi.nlm.nih.gov/pubmed/34944345
http://dx.doi.org/10.3390/ani11123570

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8697861/
https://www.ncbi.nlm.nih.gov/pubmed/34944345
http://dx.doi.org/10.3390/ani11123570

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