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Computational Insights into the Unfolding of a Destabilized Superoxide Dismutase 1 Mutant
SIMPLE SUMMARY: To function correctly, most proteins need to fold into well-defined three-dimensional structures. Destabilization of these structures may not only lead to the loss of function, but also to toxic aggregation and fibril formation. These pathological processes have been linked to a numb...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698278/ https://www.ncbi.nlm.nih.gov/pubmed/34943155 http://dx.doi.org/10.3390/biology10121240 |