Is Dosing of Ethambutol as Part of a Fixed-Dose Combination Product Optimal for Mechanically Ventilated ICU Patients with Tuberculosis? A Population Pharmacokinetic Study

Background: Tuberculosis (TB) patients admitted to intensive care units (ICU) have high mortality rates. It is uncertain whether the pharmacokinetics of first-line TB drugs in ICU patients are different from outpatients. This study aims to compare the pharmacokinetics of oral ethambutol in TB patien...

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Detalles Bibliográficos
Autores principales: Beraldi-Magalhaes, Francisco, Parker, Suzanne L., Sanches, Cristina, Sousa Garcia, Leandro, Souza Carvalho, Brenda Karoline, Fachi, Mariana Millan, de Liz, Marcus Vinicius, Pontarolo, Roberto, Lipman, Jeffrey, Cordeiro-Santos, Marcelo, Roberts, Jason A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698281/
https://www.ncbi.nlm.nih.gov/pubmed/34943771
http://dx.doi.org/10.3390/antibiotics10121559

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698281/
https://www.ncbi.nlm.nih.gov/pubmed/34943771
http://dx.doi.org/10.3390/antibiotics10121559

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