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Targeting Mycobacterial F-ATP Synthase C-Terminal α Subunit Interaction Motif on Rotary Subunit γ

Mycobacteria regulate their energy (ATP) levels to sustain their survival even in stringent living conditions. Recent studies have shown that mycobacteria not only slow down their respiratory rate but also block ATP hydrolysis of the F-ATP synthase (α(3):β(3):γ:δ:ε:a:b:b’:c(9)) to maintain ATP homeo...

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Detalles Bibliográficos
Autores principales: Harikishore, Amaravadhi, Wong, Chui-Fann, Ragunathan, Priya, Litty, Dennis, Müller, Volker, Grüber, Gerhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698299/
https://www.ncbi.nlm.nih.gov/pubmed/34943667
http://dx.doi.org/10.3390/antibiotics10121456