An Antibacterial Peptide with High Resistance to Trypsin Obtained by Substituting d-Amino Acids for Trypsin Cleavage Sites

The poor stability of antibacterial peptide to protease limits its clinical application. Among these limitations, trypsin mainly exists in digestive tract, which is an insurmountable obstacle to orally delivered peptides. OM19R is a random curly polyproline cationic antimicrobial peptide, which has...

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Detalles Bibliográficos
Autores principales: Zhao, Xiaoou, Zhang, Mengna, Muhammad, Inam, Cui, Qi, Zhang, Haipeng, Jia, Yu, Xu, Qijun, Kong, Lingcong, Ma, Hongxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698302/
https://www.ncbi.nlm.nih.gov/pubmed/34943677
http://dx.doi.org/10.3390/antibiotics10121465

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698302/
https://www.ncbi.nlm.nih.gov/pubmed/34943677
http://dx.doi.org/10.3390/antibiotics10121465

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