Mangostanaxanthone IV Ameliorates Streptozotocin-Induced Neuro-Inflammation, Amyloid Deposition, and Tau Hyperphosphorylation via Modulating PI3K/Akt/GSK-3β Pathway

SIMPLE SUMMARY: Mangostanaxanthone IV (MX-IV) is a major constituent in Garcinia mangostana. It induced neuro-protective effects in the ICV-STZ mouse model through diminishing ICV-STZ-induced oxidative stress, neuro-inflammation, and apoptosis which was reflected by a significant reduction in malond...

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Detalles Bibliográficos
Autores principales: Abdallah, Hossam M., El Sayed, Nesrine S., Sirwi, Alaa, Ibrahim, Sabrin R. M., Mohamed, Gamal A., Abdel Rasheed, Nora O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698304/
https://www.ncbi.nlm.nih.gov/pubmed/34943213
http://dx.doi.org/10.3390/biology10121298

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698304/
https://www.ncbi.nlm.nih.gov/pubmed/34943213
http://dx.doi.org/10.3390/biology10121298

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