Inhibition of MurA Enzyme from Escherichia coli and Staphylococcus aureus by Diterpenes from Lepechinia meyenii and Their Synthetic Analogs

Enzymes MurA and MurF, involved in bacterial cell wall synthesis, have been validated as targets for the discovery of novel antibiotics. A panel of plant-origin antibacterial diterpenes and synthetic analogs derived therefrom were investigated for their inhibitory properties on these enzymes from Es...

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Detalles Bibliográficos
Autores principales: Funes Chabán, Macarena, Hrast, Martina, Frlan, Rok, Graikioti, Dafni G., Athanassopoulos, Constantinos M., Carpinella, María Cecilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698320/
https://www.ncbi.nlm.nih.gov/pubmed/34943747
http://dx.doi.org/10.3390/antibiotics10121535

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698320/
https://www.ncbi.nlm.nih.gov/pubmed/34943747
http://dx.doi.org/10.3390/antibiotics10121535

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