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Red Blood Cell-Derived Iron Alters Macrophage Function in COPD

Lung macrophage iron levels are increased in COPD patients. Lung macrophage iron levels are thought to be increased by cigarette smoke, but the role of red blood cells (RBCs) as a source of iron has not been investigated. We investigate RBCs as a potential source of alveolar iron in COPD, and determ...

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Detalles Bibliográficos
Autores principales: Baker, James M., Hammond, Molly, Dungwa, Josiah, Shah, Rajesh, Montero-Fernandez, Angeles, Higham, Andrew, Lea, Simon, Singh, Dave
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698324/
https://www.ncbi.nlm.nih.gov/pubmed/34944755
http://dx.doi.org/10.3390/biomedicines9121939