Improving Generation of Cardiac Organoids from Human Pluripotent Stem Cells Using the Aurora Kinase Inhibitor ZM447439

Drug-induced cardiotoxicity reduces the success rates of drug development. Thus, the limitations of current evaluation methods must be addressed. Human cardiac organoids (hCOs) derived from induced pluripotent stem cells (hiPSCs) are useful as an advanced drug-testing model; they demonstrate similar...

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Detalles Bibliográficos
Autores principales: Lee, Su-Jin, Kim, Hyeon-A, Kim, Sung-Joon, Lee, Hyang-Ae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698385/
https://www.ncbi.nlm.nih.gov/pubmed/34944767
http://dx.doi.org/10.3390/biomedicines9121952

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698385/
https://www.ncbi.nlm.nih.gov/pubmed/34944767
http://dx.doi.org/10.3390/biomedicines9121952

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