Activation of PPARα by Fenofibrate Attenuates the Effect of Local Heart High Dose Irradiation on the Mouse Cardiac Proteome

Radiation-induced cardiovascular disease is associated with metabolic remodeling in the heart, mainly due to the inactivation of the transcription factor peroxisome proliferator-activated receptor alpha (PPARα), thereby inhibiting lipid metabolic enzymes. The objective of the present study was to in...

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Detalles Bibliográficos
Autores principales: Azimzadeh, Omid, Subramanian, Vikram, Sievert, Wolfgang, Merl-Pham, Juliane, Oleksenko, Kateryna, Rosemann, Michael, Multhoff, Gabriele, Atkinson, Michael J., Tapio, Soile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698387/
https://www.ncbi.nlm.nih.gov/pubmed/34944662
http://dx.doi.org/10.3390/biomedicines9121845

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698387/
https://www.ncbi.nlm.nih.gov/pubmed/34944662
http://dx.doi.org/10.3390/biomedicines9121845

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