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Activation of PPARα by Fenofibrate Attenuates the Effect of Local Heart High Dose Irradiation on the Mouse Cardiac Proteome
Radiation-induced cardiovascular disease is associated with metabolic remodeling in the heart, mainly due to the inactivation of the transcription factor peroxisome proliferator-activated receptor alpha (PPARα), thereby inhibiting lipid metabolic enzymes. The objective of the present study was to in...
Autores principales: | Azimzadeh, Omid, Subramanian, Vikram, Sievert, Wolfgang, Merl-Pham, Juliane, Oleksenko, Kateryna, Rosemann, Michael, Multhoff, Gabriele, Atkinson, Michael J., Tapio, Soile |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698387/ https://www.ncbi.nlm.nih.gov/pubmed/34944662 http://dx.doi.org/10.3390/biomedicines9121845 |
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