miR-6315 Attenuates Methotrexate Treatment-Induced Decreased Osteogenesis and Increased Adipogenesis Potentially through Modulating TGF-β/Smad2 Signalling

Methotrexate (MTX) treatment for childhood malignancies has shown decreased osteogenesis and increased adipogenesis in bone marrow stromal cells (BMSCs), leading to bone loss and bone marrow adiposity, for which the molecular mechanisms are not fully understood. Currently, microRNAs (miRNAs) are eme...

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Detalles Bibliográficos
Autores principales: Zhang, Ya-Li, Liu, Liang, Su, Yu-Wen, Xian, Cory J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698410/
https://www.ncbi.nlm.nih.gov/pubmed/34944742
http://dx.doi.org/10.3390/biomedicines9121926

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698410/
https://www.ncbi.nlm.nih.gov/pubmed/34944742
http://dx.doi.org/10.3390/biomedicines9121926

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