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8-Hydroxydaidzein Downregulates JAK/STAT, MMP, Oxidative Phosphorylation, and PI3K/AKT Pathways in K562 Cells

A metabolite isolated from fermented soybean, 8-hydroxydaidzein (8-OHD, 7,8,4′-trihydroxyisoflavone, NSC-678112), is widely used in ethnopharmacological research due to its anti-proliferative and anti-inflammatory effects. We reported previously that 8-OHD provoked reactive oxygen species (ROS) over...

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Detalles Bibliográficos
Autores principales: Wu, Pei-Shan, Wang, Chih-Yang, Chen, Pin-Shern, Hung, Jui-Hsiang, Yen, Jui-Hung, Wu, Ming-Jiuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698423/
https://www.ncbi.nlm.nih.gov/pubmed/34944720
http://dx.doi.org/10.3390/biomedicines9121907