DNA Methyltransferase HsdM Induce Drug Resistance on Mycobacterium tuberculosis via Multiple Effects

Besides the genomic variants, epigenetic mechanisms such as DNA methylation also have an effect on drug resistance. This study aimed to investigate the methylomes of totally/extensively drug-resistant M. tuberculosis clinical isolates using the PacBio single-molecule real-time technology. The result...

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Detalles Bibliográficos
Autores principales: Chu, Hongqian, Hu, Yongfei, Zhang, Bing, Sun, Zhaogang, Zhu, Baoli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698436/
https://www.ncbi.nlm.nih.gov/pubmed/34943756
http://dx.doi.org/10.3390/antibiotics10121544

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698436/
https://www.ncbi.nlm.nih.gov/pubmed/34943756
http://dx.doi.org/10.3390/antibiotics10121544

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