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Metformin Improves Stemness of Human Adipose-Derived Stem Cells by Downmodulation of Mechanistic Target of Rapamycin (mTOR) and Extracellular Signal-Regulated Kinase (ERK) Signaling

Adipose tissue plays an important role in regulating metabolic homeostasis by storing excess fat and protecting other organs from lipotoxicity. Aging is associated with central fat redistribution, culminating in a decrease in insulin-sensitive subcutaneous and an increase in insulin-resistant viscer...

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Detalles Bibliográficos
Autores principales: Chinnapaka, Somaiah, Yang, Katherine S., Flowers, Quinn, Faisal, Minhal, Nerone, Wayne Vincent, Rubin, Joseph Peter, Ejaz, Asim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698459/
https://www.ncbi.nlm.nih.gov/pubmed/34944598
http://dx.doi.org/10.3390/biomedicines9121782