Cargando…

Metformin Improves Stemness of Human Adipose-Derived Stem Cells by Downmodulation of Mechanistic Target of Rapamycin (mTOR) and Extracellular Signal-Regulated Kinase (ERK) Signaling

Adipose tissue plays an important role in regulating metabolic homeostasis by storing excess fat and protecting other organs from lipotoxicity. Aging is associated with central fat redistribution, culminating in a decrease in insulin-sensitive subcutaneous and an increase in insulin-resistant viscer...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chinnapaka, Somaiah, Yang, Katherine S., Flowers, Quinn, Faisal, Minhal, Nerone, Wayne Vincent, Rubin, Joseph Peter, Ejaz, Asim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698459/ https://www.ncbi.nlm.nih.gov/pubmed/34944598 http://dx.doi.org/10.3390/biomedicines9121782

Ejemplares similares

162. Establishment Of Protocol To Enable On-Site Cryopreservation Of Fat For Repeat Procedures
por: Surucu, Yusuf, et al.
Publicado: (2023)

Nicotinamide Riboside Improves Stemness of Human Adipose-Derived Stem Cells and Inhibits Terminal Adipocyte Differentiation
por: Chinnapaka, Somaiah, et al.
Publicado: (2023)

D80. Early-onset Metformin Regimen Inhibits Radiation-induced Fibrosis in Mice Model
por: Surucu, Yusuf, et al.
Publicado: (2023)

SP13. Early-Onset Metformin Regimen Inhibits Radiation-induced Fibrosis in Mice Model
por: Surucu, Yusuf, et al.
Publicado: (2023)

The Impact of Human Lipoaspirate and Adipose Tissue-Derived Stem Cells Contact Culture on Breast Cancer Cells: Implications in Breast Reconstruction
por: Ejaz, Asim, et al.
Publicado: (2020)

Cryopreserved Allogeneic Adipose Improves Neo-dermal and Epidermal Thickness after Burns
por: Loder, Shawn, et al.
Publicado: (2021)

Allogeneic adipose‐derived stem cells mitigate acute radiation syndrome by the rescue of damaged bone marrow cells from apoptosis
por: Chinnapaka, Somaiah, et al.
Publicado: (2021)

The Role of Mechanistic Target of Rapamycin (mTOR) Complexes Signaling in the Immune Responses
por: Soliman, Ghada A.
Publicado: (2013)

QS5: Cryopreserved Adipose for Hypodermal Augmentation After Full-thickness Burns
por: Loder, Shawn J., et al.
Publicado: (2021)

SP09. Allogeneic Adipose Tissue-derived Matrix Mitigate Radiation-induced Fibrosis
por: Surucu, Yusuf, et al.
Publicado: (2023)

Immunomodulatory and Antiaging Mechanisms of Resveratrol, Rapamycin, and Metformin: Focus on mTOR and AMPK Signaling Networks
por: Sorrenti, Vincenzo, et al.
Publicado: (2022)

Mechanistic Target of Rapamycin (mTOR) in the Cancer Setting
por: Murray, James T., et al.
Publicado: (2018)

Mammalian/mechanistic target of rapamycin (mTOR) complexes in neurodegeneration
por: Querfurth, Henry, et al.
Publicado: (2021)

Oncogenic Signalling through Mechanistic Target of Rapamycin (mTOR): A Driver of Metabolic Transformation and Cancer Progression
por: Rad, Ellie, et al.
Publicado: (2018)

Downregulation of cancer stem cell properties via mTOR signaling pathway inhibition by rapamycin in nasopharyngeal carcinoma
por: YANG, CHUNGUANG, et al.
Publicado: (2015)

The Mechanistic Target of Rapamycin (mTOR): Novel Considerations as an Antiviral Treatment
por: Maiese, Kenneth
Publicado: (2020)

Rapamycin Reduced Ischemic Brain Damage in Diabetic Animals Is Associated with Suppressions of mTOR and ERK1/2 Signaling
por: Liu, Ping, et al.
Publicado: (2016)

Different Patterns of Akt and ERK Feedback Activation in Response to Rapamycin, Active-Site mTOR Inhibitors and Metformin in Pancreatic Cancer Cells
por: Soares, Heloisa P., et al.
Publicado: (2013)

The Role of Mammalian Target of Rapamycin (mTOR) in Insulin Signaling
por: Yoon, Mee-Sup
Publicado: (2017)

Mechanistic Target of Rapamycin (Mtor) Is Essential for Murine Embryonic Heart Development and Growth
por: Zhu, Yi, et al.
Publicado: (2013)

mTOR Mysteries: Nuances and Questions About the Mechanistic Target of Rapamycin in Neurodegeneration
por: Norwitz, Nicholas G., et al.
Publicado: (2020)

Mechanistic target of rapamycin kinase (Mtor) is required for spermatogonial proliferation and differentiation in mice
por: Cao, Jun, et al.
Publicado: (2019)

Mechanistic target of rapamycin signaling in human nervous system development and disease
por: Girodengo, Marie, et al.
Publicado: (2022)

The Glucagon-Like Peptide 1 Receptor Agonist Liraglutide Stimulates Mechanistic Target of Rapamycin (mTOR) Signaling via PKA And Akt
por: Le, Thao D V, et al.
Publicado: (2021)

GOLPH3 modulates mTOR signaling and rapamycin sensitivity in cancer
por: Scott, Kenneth L., et al.
Publicado: (2009)

Advances in the mTOR signaling pathway and its inhibitor rapamycin in epilepsy
por: Zhao, Wei, et al.
Publicado: (2023)

Involvement of Mechanistic Target of Rapamycin (mTOR) in Valine Orexigenic Effects in Rainbow Trout
por: Comesaña, Sara, et al.
Publicado: (2022)

Recent advances of the mammalian target of rapamycin signaling in mesenchymal stem cells
por: Cai, Huarui, et al.
Publicado: (2022)

Combined Treatment with Acalabrutinib and Rapamycin Inhibits Glioma Stem Cells and Promotes Vascular Normalization by Downregulating BTK/mTOR/VEGF Signaling
por: Su, Yu-Kai, et al.
Publicado: (2021)

Enhanced activation of mechanistic target of rapamycin complex 1 signaling in eruptive xanthomas
por: Huang, Yan, et al.
Publicado: (2023)

Cyclopamine and Rapamycin Synergistically Inhibit mTOR Signalling in Mouse Hepatocytes, Revealing an Interaction of Hedgehog and mTor Signalling in the Liver
por: Spormann, Luise, et al.
Publicado: (2020)

Oxidative downmodulation of T cell-mediated cytotoxicity
por: Wabnitz, Guido H, et al.
Publicado: (2016)

Blockade of the mTOR signaling pathway with rapamycin ameliorates aristolochic acid nephropathy
por: Wu, Minmin, et al.
Publicado: (2020)

Ex pression of Concern: Different Patterns of Akt and ERK Feedback Activation in Response to Rapamycin, Active-Site mTOR Inhibitors and Metformin in Pancreatic Cancer Cells
Publicado: (2023)

Insulinoma and Tuberous Sclerosis: A Possible Mechanistic Target of Rapamycin (mTOR) Pathway Abnormality?
por: Kang, Michael Yoon, et al.
Publicado: (2017)

Propionate promotes gluconeogenesis by regulating mechanistic target of rapamycin (mTOR) pathway in calf hepatocytes
por: Wang, Guo Yan, et al.
Publicado: (2023)

Mechanistic target of rapamycin (mTOR): a potential new therapeutic target for rheumatoid arthritis
por: Zhang, Fen, et al.
Publicado: (2023)

Collagen Promotes Higher Adhesion, Survival and Proliferation of Mesenchymal Stem Cells
por: Somaiah, Chinnapaka, et al.
Publicado: (2015)

Mechanistic insights into the role of mTOR signaling in neuronal differentiation
por: Bateman, Joseph M
Publicado: (2015)

Mammalian Target of Rapamycin (mTOR) Signaling at the Crossroad of Muscle Fiber Fate in Sarcopenia
por: Sirago, Giuseppe, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_48p3il19d65ib3rcd1bjt89eoc