Thalidomide Exerts Anti-Inflammatory Effects in Cutaneous Lupus by Inhibiting the IRF4/NF-ҡB and AMPK1/mTOR Pathways

Thalidomide is effective in patients with refractory cutaneous lupus erythematosus (CLE). However, the mechanism of action is not completely understood, and its use is limited by its potential, severe side-effects. Immune cell subset analysis in thalidomide’s CLE responder patients showed a reductio...

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Detalles Bibliográficos
Autores principales: Domingo, Sandra, Solé, Cristina, Moliné, Teresa, Ferrer, Berta, Cortés-Hernández, Josefina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698478/
https://www.ncbi.nlm.nih.gov/pubmed/34944673
http://dx.doi.org/10.3390/biomedicines9121857

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698478/
https://www.ncbi.nlm.nih.gov/pubmed/34944673
http://dx.doi.org/10.3390/biomedicines9121857

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