Cargando…

Thalidomide Exerts Anti-Inflammatory Effects in Cutaneous Lupus by Inhibiting the IRF4/NF-ҡB and AMPK1/mTOR Pathways

Thalidomide is effective in patients with refractory cutaneous lupus erythematosus (CLE). However, the mechanism of action is not completely understood, and its use is limited by its potential, severe side-effects. Immune cell subset analysis in thalidomide’s CLE responder patients showed a reductio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Domingo, Sandra, Solé, Cristina, Moliné, Teresa, Ferrer, Berta, Cortés-Hernández, Josefina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698478/ https://www.ncbi.nlm.nih.gov/pubmed/34944673 http://dx.doi.org/10.3390/biomedicines9121857

Ejemplares similares

MicroRNAs in Several Cutaneous Autoimmune Diseases: Psoriasis, Cutaneous Lupus Erythematosus and Atopic Dermatitis
por: Domingo, Sandra, et al.
Publicado: (2020)

IRF-8/miR-451a regulates M-MDSC differentiation via the AMPK/mTOR signal pathway during lupus development
por: Shi, Guoping, et al.
Publicado: (2021)

An Exosomal Urinary miRNA Signature for Early Diagnosis of Renal Fibrosis in Lupus Nephritis
por: Solé, Cristina, et al.
Publicado: (2019)

AMPK–mTOR Signaling and Cellular Adaptations in Hypoxia
por: Chun, Yoomi, et al.
Publicado: (2021)

Humoral and cellular response in convalescent COVID-19 lupus patients
por: Solé, Cristina, et al.
Publicado: (2022)

Central Exercise Action Increases the AMPK and mTOR Response to Leptin
por: Ropelle, Eduardo R., et al.
Publicado: (2008)

TFEC contributes to cardiac hypertrophy by inhibiting AMPK/mTOR signaling
por: Zhao, Ting, et al.
Publicado: (2021)

The Urinary Exosomal miRNA Expression Profile is Predictive of Clinical Response in Lupus Nephritis
por: Garcia-Vives, Eloi, et al.
Publicado: (2020)

Discoid lupus erythematosus of the nail treated with thalidomide
por: Harp, Taylor, et al.
Publicado: (2023)

Feeding Uninvited Guests: mTOR and AMPK Set the Table for Intracellular Pathogens
por: Brunton, Jason, et al.
Publicado: (2013)

Retraction: Central Exercise Action Increases the AMPK and mTOR Response to Leptin
Publicado: (2018)

Alpha-ketoglutarate extends Drosophila lifespan by inhibiting mTOR and activating AMPK
por: Su, Yuan, et al.
Publicado: (2019)

Glucose activates the primordial follicle through the AMPK/mTOR signaling pathway
por: Xu, Shengyu, et al.
Publicado: (2020)

How does mTOR sense glucose starvation? AMPK is the usual suspect
por: Leprivier, Gabriel, et al.
Publicado: (2020)

Folliculin: A Regulator of Transcription Through AMPK and mTOR Signaling Pathways
por: Ramirez Reyes, Josué M. J., et al.
Publicado: (2021)

Editorial: AMPK and mTOR Beyond Signaling: Emerging Roles in Transcriptional Regulation
por: Audet-Walsh, Étienne, et al.
Publicado: (2021)

Computational modeling of AMPK and mTOR crosstalk in glutamatergic synapse calcium signaling
por: Leung, A., et al.
Publicado: (2023)

Glucogallin Attenuates RAW 264.7 Cells from Arsenic Trioxide Induced Toxicity via the NF-ҡB/NLRP3 Pathway
por: Khan, Anam Najib, et al.
Publicado: (2022)

Bilobalide Exerts Anti-Inflammatory Effects on Chondrocytes Through the AMPK/SIRT1/mTOR Pathway to Attenuate ACLT-Induced Post-Traumatic Osteoarthritis in Rats
por: Ma, Tianwen, et al.
Publicado: (2022)

A systems study reveals concurrent activation of AMPK and mTOR by amino acids
por: Pezze, Piero Dalle, et al.
Publicado: (2016)

Irisin inhibits pancreatic cancer cell growth via the AMPK-mTOR pathway
por: Liu, Jiayu, et al.
Publicado: (2018)

Berberine induces autophagy in glioblastoma by targeting the AMPK/mTOR/ULK1-pathway
por: Wang, Jiwei, et al.
Publicado: (2016)

Insight on Transcriptional Regulation of the Energy Sensing AMPK and Biosynthetic mTOR Pathway Genes
por: Sukumaran, Abitha, et al.
Publicado: (2020)

Metformin attenuates cartilage degeneration in an experimental osteoarthritis model by regulating AMPK/mTOR
por: Feng, Xiaofeng, et al.
Publicado: (2020)

Phellodendrine promotes autophagy by regulating the AMPK/mTOR pathway and treats ulcerative colitis
por: Su, Shuai, et al.
Publicado: (2021)

Dapagliflozin Alleviates Hepatic Steatosis by Restoring Autophagy via the AMPK-mTOR Pathway
por: Li, Liuran, et al.
Publicado: (2021)

Coordination of the AMPK, Akt, mTOR, and p53 Pathways under Glucose Starvation
por: Zhou, Yifan, et al.
Publicado: (2022)

Efficacy and safety of lenalidomide for refractory cutaneous lupus erythematosus
por: Cortés-Hernández, Josefina, et al.
Publicado: (2012)

Sinomenine ester derivative inhibits glioblastoma by inducing mitochondria-dependent apoptosis and autophagy by PI3K/AKT/mTOR and AMPK/mTOR pathway
por: Zheng, Xiangjin, et al.
Publicado: (2021)

Duck Tembusu virus induces incomplete autophagy via the ERK/mTOR and AMPK/mTOR signalling pathways to promote viral replication in neuronal cells
por: Wang, Qing, et al.
Publicado: (2023)

Thalidomide and discoid lupus erythematosus: case series and review of literature
por: Malara, Giovanna, et al.
Publicado: (2022)

Urinary Neuropilin-1: A Predictive Biomarker for Renal Outcome in Lupus Nephritis
por: Torres-Salido, Maria Teresa, et al.
Publicado: (2019)

Rhein Inhibits Autophagy in Rat Renal Tubular Cells by Regulation of AMPK/mTOR Signaling
por: Tu, Yue, et al.
Publicado: (2017)

Salmonella Typhimurium disrupts Sirt1/AMPK checkpoint control of mTOR to impair autophagy
por: Ganesan, Raja, et al.
Publicado: (2017)

Xiaoqinglong Decoction Protects the Lungs of AECOPD Mice through the AMPK/mTOR Signaling Pathway
por: Huang, Qingsong, et al.
Publicado: (2020)

Trifolirhizin induces autophagy-dependent apoptosis in colon cancer via AMPK/mTOR signaling
por: Sun, Dongdong, et al.
Publicado: (2020)

AMPK promotes induction of the tumor suppressor FLCN through activation of TFEB independently of mTOR
por: Collodet, Caterina, et al.
Publicado: (2019)

Trimetazidine ameliorates sunitinib-induced cardiotoxicity in mice via the AMPK/mTOR/autophagy pathway
por: Yang, Yi, et al.
Publicado: (2019)

AMPK/mTOR Signaling in Autophagy Regulation During Cisplatin-Induced Acute Kidney Injury
por: Wang, Ying, et al.
Publicado: (2020)

Periplocin inhibits the growth of pancreatic cancer by inducing apoptosis via AMPK‐mTOR signaling
por: Xie, Gangyin, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_u4bj816vof8qdc2vrfokur8cpa