WPK5, a Novel Kunitz-Type Peptide from the Leech Whitmania pigra Inhibiting Factor XIa, and Its Loop-Replaced Mutant to Improve Potency

Kunitz-type proteins or peptides have been found in many blood-sucking animals, but the identity of them in leeches remained elusive. In the present study, five Kunitz-type peptides named WPK1-WPK5 were identified from the leech Whitmania pigra. Recombinant WPK1-WPK5 were expressed in Pichia pastori...

Descripción completa

Detalles Bibliográficos
Autores principales: Zheng, Yi-Zheng, Ji, Xiao-Ru, Liu, Yun-Yang, Jiang, Shuai, Yu, Xiang-Ying, Jia, Zhi-Ping, Zhao, Yue, Zhang, Jun-Qiao, Zhang, Jia-Li, Kong, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698482/
https://www.ncbi.nlm.nih.gov/pubmed/34944561
http://dx.doi.org/10.3390/biomedicines9121745

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698482/
https://www.ncbi.nlm.nih.gov/pubmed/34944561
http://dx.doi.org/10.3390/biomedicines9121745

Ejemplares similares