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Synthesis of novel seven-membered carbasugars and evaluation of their glycosidase inhibition potentials

Here, we report the synthesis of five novel seven-membered carbasugar analogs. We adopted a chiral-pool strategy starting from the cheap and readily available d-mannitol to synthesize these ring-expanded carbasugars. Apart from several regioselective protecting group manipulations, these syntheses i...

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Detalles Bibliográficos
Autores principales: Athiyarath, Vignesh, Roy, Naveen J., Vijil, A. T. V., Sureshan, Kana M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698521/
https://www.ncbi.nlm.nih.gov/pubmed/35423467
http://dx.doi.org/10.1039/d1ra00804h