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Synthesis of novel seven-membered carbasugars and evaluation of their glycosidase inhibition potentials
Here, we report the synthesis of five novel seven-membered carbasugar analogs. We adopted a chiral-pool strategy starting from the cheap and readily available d-mannitol to synthesize these ring-expanded carbasugars. Apart from several regioselective protecting group manipulations, these syntheses i...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698521/ https://www.ncbi.nlm.nih.gov/pubmed/35423467 http://dx.doi.org/10.1039/d1ra00804h |