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High Glucose Concentrations Impair the Processing and Presentation of Mycobacterium tuberculosis Antigens In Vitro

Type 2 diabetes is an established risk factor for tuberculosis, but the underlying mechanisms are largely unknown. We established an in vitro model to analyze the effect of high glucose concentrations in antigen processing and presentation in antigen-presenting cells. Human monocyte-derived macropha...

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Detalles Bibliográficos
Autores principales: Monroy-Mérida, Guadalupe, Guzmán-Beltrán, Silvia, Hernández, Fernando, Santos-Mendoza, Teresa, Bobadilla, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698639/
https://www.ncbi.nlm.nih.gov/pubmed/34944407
http://dx.doi.org/10.3390/biom11121763