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Divergent Effects of EZH1 and EZH2 Protein Expression on the Prognosis of Patients with T-Cell Lymphomas

T-cell lymphomas are highly heterogeneous and their prognosis is poor under the currently available therapies. Enhancers of zeste homologue 1 and 2 (EZH1/2) are histone H3 lysine-27 trimethyltransferases (H3K27me3). Despite the rapid development of new drugs inhibiting EZH2 and/or EZH1, the molecula...

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Detalles Bibliográficos
Autores principales: Schümann, Franziska Lea, Groß, Elisabeth, Bauer, Marcus, Rohde, Christian, Sandmann, Sarah, Terziev, Denis, Müller, Lutz P., Posern, Guido, Wienke, Andreas, Fend, Falko, Hansmann, Martin-Leo, Klapper, Wolfram, Rosenwald, Andreas, Stein, Harald, Dugas, Martin, Müller-Tidow, Carsten, Wickenhauser, Claudia, Binder, Mascha, Weber, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698684/
https://www.ncbi.nlm.nih.gov/pubmed/34944658
http://dx.doi.org/10.3390/biomedicines9121842