Analyzing the Therapeutic Efficacy of Bis-Choline-Tetrathiomolybdate in the Atp7b(−/−) Copper Overload Mouse Model

Bis-choline-tetrathiomolybdate, introduced as WTX101 (now known as ALXN1840), is a first-in-class copper-protein-binding agent for oral therapy of Wilson’s disease. In contrast to other decoppering agents such as trientine or D-penicillamine it acts by forming a tripartite complex with copper and al...

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Detalles Bibliográficos
Autores principales: Kim, Philipp, Zhang, Chengcheng Christine, Thoröe-Boveleth, Sven, Buhl, Eva Miriam, Weiskirchen, Sabine, Stremmel, Wolfgang, Merle, Uta, Weiskirchen, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698685/
https://www.ncbi.nlm.nih.gov/pubmed/34944677
http://dx.doi.org/10.3390/biomedicines9121861

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698685/
https://www.ncbi.nlm.nih.gov/pubmed/34944677
http://dx.doi.org/10.3390/biomedicines9121861

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