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Analyzing the Therapeutic Efficacy of Bis-Choline-Tetrathiomolybdate in the Atp7b(−/−) Copper Overload Mouse Model
Bis-choline-tetrathiomolybdate, introduced as WTX101 (now known as ALXN1840), is a first-in-class copper-protein-binding agent for oral therapy of Wilson’s disease. In contrast to other decoppering agents such as trientine or D-penicillamine it acts by forming a tripartite complex with copper and al...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698685/ https://www.ncbi.nlm.nih.gov/pubmed/34944677 http://dx.doi.org/10.3390/biomedicines9121861 |