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A Mitochondria-Penetrating Peptide Exerts Potent Anti-Plasmodium Activity and Localizes at Parasites’ Mitochondria

Mitochondria are considered a novel drug target as they play a key role in energy production and programmed cell death of eukaryotic cells. The mitochondria of malaria parasites differ from those of their vertebrate hosts, contributing to the drug selectivity and the development of antimalarial drug...

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Detalles Bibliográficos
Autores principales: Somsri, Sangdao, Mungthin, Mathirut, Klubthawee, Natthaporn, Adisakwattana, Poom, Hanpithakpong, Warunee, Aunpad, Ratchaneewan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698686/
https://www.ncbi.nlm.nih.gov/pubmed/34943772
http://dx.doi.org/10.3390/antibiotics10121560