α-Synuclein Overexpression Increases Dopamine D2/3 Receptor Binding and Immune Activation in a Model of Early Parkinson’s Disease

Progressive degeneration of dopaminergic neurons, immune activation, and α-synuclein pathology characterize Parkinson’s disease (PD). We previously reported that unilateral intranigral injection of recombinant adeno-associated viral (rAAV) vectors encoding wild-type human α-synuclein produced a rat...

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Detalles Bibliográficos
Autores principales: Stokholm, Kathrine, Thomsen, Majken Borup, Phan, Jenny-Ann, Møller, Line K., Bay-Richter, Cecilie, Christiansen, Søren H., Woldbye, David P. D., Romero-Ramos, Marina, Landau, Anne M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698691/
https://www.ncbi.nlm.nih.gov/pubmed/34944691
http://dx.doi.org/10.3390/biomedicines9121876

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698691/
https://www.ncbi.nlm.nih.gov/pubmed/34944691
http://dx.doi.org/10.3390/biomedicines9121876

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