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Circadian Gene PER2 Silencing Downregulates PPARG and SREBF1 and Suppresses Lipid Synthesis in Bovine Mammary Epithelial Cells

SIMPLE SUMMARY: The present study was constructed to determine the effects of the core circadian clock gene, Period 2 (PER2), on lipid synthesis in bovine mammary epithelial cells (BMECs). Data revealed that PER2-regulated genes were involved in fatty acid de novo synthesis, desaturation, TAG accumu...

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Detalles Bibliográficos
Autores principales: Jing, Yujia, Chen, Yifei, Wang, Shan, Ouyang, Jialiang, Hu, Liangyu, Yang, Qingyong, Wang, Mengzhi, Zhang, Bin, Loor, Juan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698707/
https://www.ncbi.nlm.nih.gov/pubmed/34943141
http://dx.doi.org/10.3390/biology10121226